When it comes to microdosing mushrooms, one of the first questions people ask is: "How often should I take them?" It's a smart question—and the answer depends on your goals, body, and lifestyle. Whether you're looking to boost focus, relieve stress, improve mood, or reduce reliance on alcohol and pharmaceuticals, understanding how to microdose safely and effectively is crucial.
Microdosing isn’t about “tripping” or escaping reality. It's about feeling more like yourself—clearer, calmer, and more balanced. Done right, it can enhance creativity, improve emotional resilience, and even support healthier habits. But like any wellness practice, it’s important to approach microdosing with knowledge, intention, and safety in mind.
What Is Microdosing?
Microdosing involves taking a very small, sub-perceptual dose of a psychedelic substance, typically psilocybin mushrooms. At these low doses (usually 0.1 to 0.3 grams), you won’t experience hallucinations or major alterations in perception. Instead, many people report subtle benefits like improved mood, sharper focus, and reduced anxiety.
Dr. Julie explains:
"Microdosing works by interacting with serotonin receptors in the brain, helping regulate mood, cognition, and emotional balance. When used correctly, it’s a valuable tool for enhancing daily life without the intensity of a full psychedelic experience."
How Often Should You Microdose?
There are several protocols that people use to find the right rhythm for microdosing. The best schedule for you depends on your goals, lifestyle, and how your body responds. Below are three of the most popular approaches.
1. The Fadiman Protocol (1 Day On, 2 Days Off)
- Schedule: Take a microdose on Day 1, rest on Days 2 and 3, repeat.
- Why it works: Prevents tolerance buildup and gives you time to reflect on how you feel.
- Best for: Beginners and those seeking mood stability without daily dosing.
Dr. Julie says:
"The Fadiman protocol allows your body to reset between doses, which is essential for sustainable, long-term benefits."
Who is Dr. James Fadiman?
Dr. James Fadiman is often called the “father of microdosing.” A psychologist and researcher, he has been studying the effects of psychedelics since the 1960s. His groundbreaking work brought microdosing into mainstream conversation through his book The Psychedelic Explorer’s Guide. Dr. Fadiman’s research focuses on how small doses of psychedelics can enhance mood, creativity, and overall well-being without the hallucinogenic effects. His protocol—dosing once every three days—remains one of the most widely used and studied microdosing schedules worldwide.
2. The Stamets Stack (4 Days On, 3 Days Off)
- Schedule: Microdose for four consecutive days, then take three days off.
- Includes: Psilocybin + Lion’s Mane (for neurogenesis) + Niacin (to enhance absorption).
- Best for: Cognitive enhancement, creativity boosts, and neuroplasticity support.
Dr. Julie notes:
"This method supports cognitive health and is popular among people looking to improve focus and mental clarity."
Who is Paul Stamets?
Paul Stamets is a world-renowned mycologist, author, and advocate for the medicinal use of mushrooms. With over four decades of research under his belt, he’s considered one of the leading voices in fungal science and biodiversity preservation. Stamets developed the popular “Stamets Stack” microdosing protocol, which combines psilocybin mushrooms, Lion’s Mane, and niacin to promote brain health and neurogenesis. His TED Talks and books, like Mycelium Running and Fantastic Fungi, have inspired a global movement toward understanding and harnessing the power of mushrooms for both personal health and environmental solutions.
3. The Workaholics Protocol (5 Days On, 2 Days Off)
- Schedule: Microdose Monday through Friday, rest on weekends.
- Why it’s popular: Fits seamlessly with workweeks, promoting sustained energy and focus.
- Best for: Busy professionals aiming to improve productivity while reducing coffee or alcohol reliance.
Tonya’s insight:
"We created this protocol for our customers who want to ditch that third cup of coffee and feel energized through their workweek—without crashing."
How to Find Your Ideal Dose
Everyone’s body is different. A common starting microdose is 0.1 to 0.3 grams of dried psilocybin mushrooms, but factors like metabolism, body weight, and sensitivity play a role. Start low and adjust gradually.
- ✅ Start with 0.1g if you’re new or sensitive.
- ✅ Wait an hour after dosing—if you feel nothing, increase slightly next time.
- ✅ Avoid increasing doses too quickly to prevent unwanted effects.
Dr. Julie recommends:
"Keep a journal to track your mood, focus, and sleep patterns. This helps identify what works best for your body."
Factors That Influence Microdosing Frequency
Finding the right frequency isn’t just about following a schedule—it’s about tuning into your lifestyle and body. Here’s what to consider:
- Tolerance: Psilocybin tolerance builds quickly; rest days are essential.
- Mental Health: Those with anxiety, depression, or medications (like SSRIs) should consult a healthcare provider first.
- Lifestyle Factors: Stress levels, diet, and sleep patterns can affect your experience.
Legal Considerations
In Colorado, thanks to the Natural Medicine Health Act, adults can legally possess and cultivate psilocybin for personal use. However, it’s still illegal at the federal level and in many states, so always check local laws.
Dr. Julie cautions:
"Always consult a healthcare provider if you’re on medications or have underlying conditions. Safety should always come first."
Why Microdose With SOSS?
At SOSS, our products are safe, local, and real—crafted with Colorado-grown mushrooms and third-party tested for purity. We use our own products, and we believe in solutions that support real people with real lives. This isn’t just business; it’s personal.
Tonya shares:
"Microdosing helped me stay calm, focused, and present—both at work and with my family. I’ve seen firsthand how it changes lives."
Ready to Start Your Microdosing Journey?
Choosing the right schedule is about more than timing—it’s about finding what helps you feel your best. If you’re ready to explore microdosing with personalized guidance, we’re here to help.